. Pasteur entered primary school in 1. He was an average student in his early years, and not particularly academic, as his interests were fishing and sketching. He drew many pastels and portraits of his parents, friends and neighbors. Pasteur attended secondary school at the Collge dArbois. In October 1. 83. Paris to join the Pension Barbet, but became homesick and returned in November. In 1. 83. 9, he entered the Collge Royal de Besanon to study philosophy and earned his Bachelor of Letters degree in 1. He was appointed a tutor at the Besanon college while continuing a degree science course with special mathematics. He failed his first examination in 1. He managed to pass the baccalaurat scientifique general science degree in 1. Dijon but with a mediocre grade in chemistry. Later in 1. 84. 2, Pasteur took the entrance test for the cole Normale Suprieure. He passed the first set of tests, but because his ranking was low, Pasteur decided not to continue and try again next year. He went back to the Pension Barbet to prepare for the test. He also attended classes at the Lyce Saint Louis and lectures of Jean Baptiste Dumas at the Sorbonne. In 1. 84. 3, he passed the test with a high ranking and entered the cole Normale Suprieure. In 1. 84. 5 he received the licenci s sciences Master of Science degree. In 1. 84. 6, he was appointed professor of physics at the Collge de Tournon now called Lyce Gabriel Faure fr in Ardche, but the chemist Antoine Jrme Balard wanted him back at the cole Normale Suprieure as a graduate laboratory assistant agrg prparateur. He joined Balard and simultaneously started his research in crystallography and in 1. After serving briefly as professor of physics at the Dijon Lyce in 1. University of Strasbourg,2. Marie Laurent, daughter of the universitys rector in 1. They were married on May 2. Career. Pasteur was appointed professor of chemistry at the University of Strasbourg in 1. In 1. 85. 4, he was named dean of the new faculty of sciences at Lille University, where he began his studies on fermentation. It was on this occasion that Pasteur uttered his oft quoted remark dans les champs de lobservation, le hasard ne favorise que les esprits prpars In the field of observation, chance favors only the prepared mind. In 1. 85. 7, he moved to Paris as the director of scientific studies at the cole Normale Suprieure where he took control from 1. The examinations became more rigid, which led to better results, greater competition, and increased prestige. Many of his decrees, however, were rigid and authoritarian, leading to two serious student revolts. During the bean revolt he decreed that a mutton stew, which students had refused to eat, would be served and eaten every Monday. On another occasion he threatened to expel any student caught smoking, and 7. In 1. 86. 3, he was appointed professor of geology, physics, and chemistry at the cole nationale suprieure des Beaux Arts, a position he held until his resignation in 1. In 1. 86. 7, he became the chair of organic chemistry at the Sorbonne,3. In 1. 86. 7, the cole Normales laboratory of physiological chemistry was created at Pasteurs request,3. In Paris, he established the Pasteur Institute in 1. Research. Molecular asymmetry. Pasteur separated the left and right crystal shapes from each other to form two piles of crystals in solution one form rotated light to the left, the other to the right, while an equal mixture of the two forms canceled each others effect, and does not rotate the polarized light. In Pasteurs early work as a chemist, beginning at the cole Normale Suprieure, and continuing at Strasbourg and Lille, he examined the chemical, optical and crystallographic properties of a group of compounds known as tartrates. He resolved a problem concerning the nature of tartaric acid in 1. A solution of this compound derived from living things rotated the plane of polarization of light passing through it. Dracula X English Patch here. The problem was that tartaric acid derived by chemical synthesis had no such effect, even though its chemical reactions were identical and its elemental composition was the same. Pasteur noticed that crystals of tartrates had small faces. Then he observed that, in racemic mixtures of tartrates, half of the crystals were right handed and half were left handed. In solution, the right handed compound was dextrorotatory, and the left handed one was levorotatory. Pasteur determined that optical activity related to the shape of the crystals, and that an asymmetric internal arrangement of the molecules of the compound was responsible for twisting the light. The 2. R,3. R and 2. S,3. S tartrates were isometric, non superposable mirror images of each other. This was the first time anyone had demonstrated molecular chirality, and also the first explanation of isomerism. Some historians consider Pasteurs work in this area to be his most profound and most original contributions to science, and his greatest scientific discovery. Fermentation and germ theory of diseases. Pasteur was motivated to investigate fermentation while working at Lille. In 1. 85. 6 a local wine manufacturer, M. Bigot, whose son was one of Pasteurs students, sought for his advice on the problems of making beetroot alcohol and souring. According to his son in law, Ren Vallery Radot, in August 1.